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ACRYCOATER  

Pharma coating polymers based on polyacrylates.    

ACRYCOATERS  are film former  co-polymers, which confirms to USP/NF & EP specification. ACRYCOATER   is used for film coating, enteric coating and sustained release formulation and also as a binder for tablets and transdermal therapeutic systems. 
  

Product Specifications
ACRYCOATER L100 Methacrylic acid co-polymer type "A"
ACRYCOATER S100 Methacrylic acid co-polymer type "B"
ACRYCOATER L30D Methacrylic acid co-polymer type "C"
ACRYCOATER L100D Methacrylic acid co-polymer type "C"
ACRYCOATER E30D Polyacrylate dispersion 30%.

   
This product is replacement for EUDRAGIT, HPMC, CAP,HPMC-P & ETHYL CELLULOSE etc. 
 

ACRYCOATER L100 :

ACRYCOATER L100 is an anionic co-polymer, which conforms to USP/NF specification of "METHACRYLIC ACID CO-POLYMER " TYPE  A.  The film of ACRYCOATER L100 is insoluble in gastric fluid and natural juices, and freely soluble in intestinal in pH 6.0 and above by formation of salts with alkalis. ACRYCOATER L100 film is transparent, colourless and brittle and colour can be developed by addition of pigments, if you desire to improve the elasticity, plasticizer can be used for the same. 

USES : 
Enteric coating of tablets, pills, pellets, granules and powders. 

SPECIFICATION : 
Appearance   - White, fine, free flowing  powder. 
Odour           - Weakly aromatic. 
Content         - Min. 95% dry polymer. 
Acid  value    - 300 - 330 mg KOH/gm. dry substance. 
Solubility       - Isopropyl alcohol, acetone, methanol, ethanol, methanol/ water etc. 

TOXICITY : 
ACRYCOATER L100 is a high molecular weight polymer. It is not absorbed by body tissues and is totally safe for human oral consumption. Test for toxicological tolerance show that it does not have any pronounced physiological action and is non-toxic. 

GRADES : 
ACRYCOATER L100 - Powder form 
ACRYCOATER L12.5 - Containing 12.5% dry polymer in isopropanol solutions. 
ACRYCOATER L12.5P - Containing 12.5% dry polymer and 1.25% dibutyl phalate plasticizer in Isopropanol solution. 
 
PLASTICIZER : 
ACRYCOATER L100 film is brittle in nature. So to improve film elasticity, use of plasticizer is strongly recommended. The recommended plasticizers are polyethylene glycol, dibutyl phthalate, triacetin, triethyl  citrate etc. Usually, 10% of plasticizer will be sufficient, but if necessary, can be increased to 25%. 

AVERAGE  REQUIREMENT : 
40 gms, ACRYCOATER L100 per 1 kg. tablets for enteric coating. 

PACKING : 
5 kg. 20 kg. net. In corrugated boxes lined with polyethylene. 
   

ACRYCOATER L30D :

ACRYCOATER L30D is 30%  dispersion of an anionic  acrylic co-polymers which conforms to USP/NF,  specification as   " METHACRYLIC ACID CO-POLYMER " TYPE C. The film of ACRYCOATER L30D is insoluble in gastric fluid and soluble in intestinal tract pH 5.5 and above by formation of salt with alkalis. ACRYCOATER L30D film is colourless, transparent and brittle in nature. To improve elasticity the use of plasticizer is  strongly recommended. 

This is an aqueous based system so  water soluble plasticizer should be used.  

USES : 
ACRYCOATER L30D is used  for aqueous film coating and enteric film coating of  tablets, pellets, pills, crystals and granules.

SPECIFICATION : 
Appearance   - White, milky liquid. 
Odour           - Weakly aromatic 
Content         - 28.5 to 31.5% w/w dry polymer. 
Acid value     - 300 - 330 mg KOH/gm dry substances. 
Solubility       - Water or organic alcohols, & acetone. 

TOXICITY : 
ACRYCOATER L30D is a high molecular weight polymer. It is not absorbed by body tissues and is totally safe for human oral consumption.  Test for toxicological tolerance shows that it does not have any pronounced physiological action and is non-toxic. 

PLASTICIZER : 
ACRYCOATER L30D film is brittle in nature. To improve film elasticity, use of plasticizer is strongly recommended.  The recommended plasticizers are poly-ethylene glycol, triacetin, triethyl citrate etc. Usually 10% of plasticizer will be sufficient, but if necessary, it can be increased to 25%. 

AVERAGE REQUIREMENT : 
165 gms. ACRYCOAT L30D per 1 kg. tablets for enteric coating. 
20 gms. ACRYCOAT L30D per 1 kg. tablets for film coating. 

PACKING : 
5  Kg, 30 Kg, net  in HDPE drums. 
  

ACRYCOATER L100D :

Acrycoater L100D is 100% spray dried free flowing powder of Acrycoat L30D drying, It is an anionic acrylic copolymer, which conforms to USP/NF, specification as "METHACRYLIC ACID CO-POLYMER " TYPE C. The film of Acrycoat L100D is insoluble in gastric fluid and soluble in intestinal track pH 5.5 and above by formation of salt with Alkalies. Acrycoat L100D film is colourless transperent and britle in nature. To improve elasticity the use of plasticizer is strongly recommended. 

This is a base aqueous coating system. So water soluble plasticizer should be used. It is also possible to obtain similar results using solvent/hydroalcoholic based coating. 
 

USES : 
Acrycoater L100D is used for aqueous film coating and enteric coating of tablets, pellets, pills, crystals and granules. 

SPECIFICATION : 
Appearance : White free flowing powder. 
Odur           : Weakly aromatic. 
Acid value   : 300-330 mg KOH/gm dry substances. 
Solubility     : Mixes with water and soluble in organic alcohols  
                    & Acetone. 

TOXICITY : 
ACRYCOATER L100D is a high molecular weight polymer. It is not absorbed by body tissues and is totally safe for human oral consumption.  Test for toxicological tolerance shows that it does not have any pronounced physiological action and is non-toxic. 

PLASTICIZER : 
ACRYCOATER L100D film is brittle in nature. To improve film elasticity the use of plasticizer is strongly recommended.  The recommended plasticizers are poly-ethylene glycol, triacetin, triethyl citrate etc. Usually 10% of plasticizer will be sufficient, but if necessary, can be increased to 25%. 

AVERAGE REQUIREMENT : 
40 gms Acrycoat L100D per 1kg tablet for enteric coating. 
05 gms Acrycoat L100D per 1kg tablet for film coating. 

PACKING : 
5 kg - 20 kg net in corrugated boxes lined with polyethylene.   

ACRYCOATER E30D :

ACRYCOATER E30D is a  neutral co-polymer of 30% aqueous dispersion which conforms to PH. EUROPE. 

ACRYCOATER E30D is pH independent. The  films are formed which swell in water, buffer  or gastric  fluid and are permeable in these fluids. ACRYCOATER E30D  film impart plasticizing effect and thus there is no need to add plasticizer. 

The film of ACRYCOATER E30D is colourless, transparent, elastic and break  proof.  ACRYCOATER E30D can be  miscibe  with water and soluble in solvents. 
  
USES : 
ACRYCOATER E30D is used for film coating, sustained release formulation, & wet granulation as a binder of tablet. 

For pH independent film coating, sustained release coating of tablets/pellets/granules/powder. In granulation to isolate incompatible ingredients and optimizing mechanical properties.

As a binder or film former in the manufacture of porous matrix tablets (wet granuleaion) with delay release of the active substance.

In transdermal systems to regulate release of drugs.
 

SPECIFICATION : 
Appearance  - White, milky liquid. 
Odour          - Aromatic 
Content        - 28.5 to 31.5% w/w dry polymer. 
Acid value    - Nil 
Solubility     - Water or organic solvent - alcohols, acetone. 

TOXICITY : 
ACRYCOATER E30D is a high molecular weight polymer. It is not absorbed by body tissues  and is totally safe for human oral consumption. Test for  toxicological tolerance shows that it does not have any pronounced physiological action and is non-toxic. 

PLASTICIZER : 
Plasticizer is not necessary but permeabilities of polymer can be regulated by addition of polyethylene glycols, vinyl alcohol or pyrolidone as water  soluble additives. 

AVERAGE REQUIREMENT : 
35 gms ACRYCOATER E30D per 1 kg. tablets for film coating. 
400 gms ACRYCOATER E30D per 1 kg. tablets for sustained release. 

PACKING : 
5  Kg, 30 Kg, net  in  HDPE  drums. 
   

ACRYCOATER S100 :

ACRYCOATER S100 is an anionic acrylic co-polymer which conforms to USP/NF specifications of "METHACRYLIC CO-POLYMER" TYPE B. ACRYCOAT  S100 film is resistant to grastric fluid and natural juices  but is freely soluble in intestinal tract in pH 7.0 and above by formation of salt with alkalis. Sustained release ( delay release ) effect can be developed using ACRYCOAT S100 by matrix method ( wet granulation). 

The films of ACRYCOAT S100 are colourless, transparent and brittle. Coloured film can be developed with addition of pigment use of plasticizers which is strongly recommended to improve elasticity. 

USES : 
For sustained release  or slow release enteric film coating of tablet, pellets, granules, pills, powder etc.. 

SPECIFICATION : 
Appearance  - White, fine, free flowing powder. 
Odour          - Weakly aromatic 
Content        - Min. 95% dry polymer. 
Acid value    - 180 - 200 mg. KOH/gm dry substance. 
Solubility     - Isopropyl alcohol, acetone, methanol, ethanol, methanol/water etc. 

TOXICITY : 
ACRYCOATER S100 is a high molecular weight polymer. It is not absorbed by body  tissues and is totally safe for human oral consumption. Test for toxicological tolerance shows that it does not have any pronounced physiological action and is non-toxic. 

PLASTICIZER : 
ACRYCOATER S100 film is brittle. To improve film elasticity, the use of plasticizer is strongly recommended. 

The recommended plasticizers are poly-ethylene glycol, dibutyl phthalate, diethyl phthalate, triacetin, triethyl citrate etc. Usually 10% of plasticizer will be sufficient, but if necessary, can be increased to 25%. 

AVERAGE REQUIREMENT : 
40 gms. ACRYCOATER  S100 per 1 kg. tablets for enteric coating. 
120 gms. ACRYCOATER  S100 per 1 kg. tablets for sustained release. 

PACKING : 
5 kgs, 20 kgs net in corrugated boxes lined with polyethylene. 

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